A pyrogen is, by definition, a substance that produces a rise in temperature in a human or animal. Pyrogens are differentiated into exogenous and endogenous pyrogens:

Good examples of pyrogen producing gram- negative bacteria are Escherichia coli, Proteus, Pseudomonas, Enterobacter and Klebsiella.

pyrogen Any substance that causes fever. Endogenous pyrogens are proteins, such as interleukin-1, released by white blood cells in response to bacterial or viral infections.

Fever is a highly significant indicator of disease. …system’s responses is to produce pyrogens. These chemicals are carried by the blood to the brain, where they disturb the functioning of the …

Pyrogen (fever), a fever inducing substance.

The meaning of PYROGEN is a fever-producing substance.

Pyrogen is a self-generated Aerosol Fire Extinguishing Agent, and is one of the most efficient Halon Alternative products currently available.

A pyrogen is any substance or agent that induces fever when it enters the body. It causes an elevation in the body's temperature set point, typically by acting on the hypothalamus (the …

Learn more about what pyrogens are, how pyrogen testing has developed over time, and how different pyrogen tests compare against each other.

Fever is a well-known effect, hence the term "pyrogen." About one hour after the injection of pyrogens into rabbits (or man), there is a rise in body temperature.