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  1. Drug addiction (substance use disorder) - Mayo Clinic

    Jun 20, 2025 · The risk of addiction and how fast you become addicted varies by drug. Some drugs, such as opioid painkillers, have a higher risk and cause addiction more quickly than …

  2. Kratom: Unsafe and ineffective - Mayo Clinic

    Jun 18, 2024 · The U.S. Drug Enforcement Administration calls kratom a drug of concern. Poison control centers in the United States received more than 3,400 reports about use of kratom …

  3. Prescription drug abuse - Symptoms and causes - Mayo Clinic

    Oct 25, 2022 · Prescription drug abuse in older adults is a growing problem, especially when they combine drugs with alcohol. Having multiple health problems and taking multiple drugs can put …

  4. Methadone (oral route) - Side effects & dosage - Mayo Clinic

    Oct 1, 2025 · These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or …

  5. Naltrexone (oral route) - Side effects & dosage - Mayo Clinic

    Aug 1, 2025 · These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or …

  6. Xylazine - Mayo Clinic

    Feb 14, 2024 · However, xylazine is now being used as a recreational drug. Xylazine is often mixed with heroin, fentanyl and other opioids that are taken illegally. Mixing these drugs with …

  7. Tapentadol (oral route) - Side effects & dosage

    Nov 1, 2025 · These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or …

  8. Ambien: Is dependence a concern? - Mayo Clinic

    Feb 7, 2025 · But zolpidem can have concerning side effects. For example, some people who take zolpidem or medicines like it do things while asleep that they don't remember, such as …

  9. Buprenorphine/naloxone (oromucosal route, sublingual route)

    Nov 1, 2025 · These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or …

  10. Naltrexone (intramuscular route) - Side effects & uses

    Aug 1, 2025 · It will not produce any opioid-like effects or cause mental or physical dependence. It will not prevent you from becoming impaired while drinking alcohol or using opioids. …