Kinesin is an ATP-driven molecular motor protein that moves processively along microtubules. Despite considerable research, the detailed mechanism of kinesin motion remains elusive. We applied an ...
A mobile state of the kinesin–ADP head is discovered using multi- and single-molecule fluorescence polarization. The structure of the microtubule–kinesin complex has been determined by cryo-EM. The ...
You may not know what it is, but you burn more than your body weight of it every day. Adenosine triphosphate (ATP), a tiny molecule that packs a powerful punch, is the primary energy source for most ...
Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...
A research team has uncovered a previously unknown type of immune signaling molecule—a novel compound combining histidine and ADP-ribose—produced by bacteria's Thoeris II defense system in response to ...
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