ANN ARBOR—University of Michigan researchers have learned how to fix a cellular structure called the Golgi that mysteriously becomes fragmented in all Alzheimer's patients and appears to be a major ...

Alzheimer's disease (AD) progresses inside the brain in a rising storm of cellular chaos as deposits of the toxic protein, amyloid-beta (Aβ), overwhelm neurons. An apparent side effect of ...

In this literature review, the authors show how accumulation of amyloid beta peptides leads to Golgi fragmentation. First described in 1906 by Alois Alzheimer, Alzheimer's disease (AD) represents the ...

Researchers have learned how to fix a cellular structure called the Golgi that mysteriously becomes fragmented in all Alzheimer's patients and appears to be a major cause of the disease. They say that ...

“Our study provides a molecular mechanism for Golgi fragmentation and its effects on APP [amyloid precursor protein] trafficking and processing in AD, suggesting Golgi as a potential drug target for ...

In a recent study posted to the bioRxiv* preprint server, researchers observed that Golgi fragmentation induced by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) facilitates viral ...

Obligate intracellular parasites obtain nutrients from the host cell, but the mechanisms by which this occurs are often poorly understood. Writing in Nature, Heuer and colleagues now show that ...

In the United States, prostate cancer (PCa) is the second-leading cause of cancer death in men. Multiple observations indicate the link between prostate carcinogenesis, stress of endoplasmic reticulum ...

Researchers have identified that the status of the T-cell Golgi apparatus is a key indicator of performance in cancer immunotherapy approaches. A group of researchers working at the Medical University ...

Alzheimer's disease (AD) progresses inside the brain in a rising storm of cellular chaos as deposits of the toxic protein, amyloid-beta (Aβ), overwhelm neurons. An apparent side effect of accumulating ...

Alzheimer's disease (AD) progresses inside the brain in a rising storm of cellular chaos as deposits of the toxic protein, amyloid-beta (Aβ), overwhelm neurons. An apparent side effect of accumulating ...